FIELD: biotechnology, veterinary microbiology. SUBSTANCE: vaccine has high-immunogenic strain of Chlamydia psittaci K-8-K VIEV at titer 108,5-9,0ELD50/0.2 ml taken at effective amount. Vaccine can contain light mineral oil and anhydrous lanolin as adjuvant at ratio = (87:13)-(90:10), or aerosil and saponine and formalin as an inactivating agent. Used strain is adapted to culturing in transplanted cell line of saiga kidney. Strain can be accumulated at higher titers as compared with that at culturing in chicken embryos. Obtained antigen does not contain inert proteins and does not require the additional purification and concentrating. EFFECT: enhanced effectiveness of vaccine. 3 cl
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Authors
Dates
1997-07-27—Published
1995-06-05—Filed