FIELD: medicine. SUBSTANCE: present invention of novel nitric acid such as cyclohexanol derivatives of general formula I: 
wherein A denotes valency, or C1-C6- alkylene chain; B is NR1-CO-Z, -NR1SO2-Z or -CO-NR2-I; R1 is hydrogen or C1-C6 alkyl group; R2 is hydrogen, hydroxy-C1-C6-alkyl, C1-C6 alkyl, C2-C6-alkenyl; and Z is hydrogen, C1-C6-alkyl, C2-C6- alkenyl or C2-C6-alkynyl which can be mono-or multisubstituted for hydroxy; C1-C6-alkylcarbonyloxy, C1-C6- alkoxy; halogen-cyano, carboxy-, C1-C6 alkoxycarbonyl-, CO-NR3R4 or C1-C6-alkylcarbonylmercapto group or Z is pyridine, N- oxypyridine-or pyrrolidine ring, or Z together with R2 and nitrogen atom, to which Z and R2 are attached form heterocyclic ring which further contain oxygen atom; R3 and R4 are C1-C6-alkyl or hydrogen, and also optically active forms thereof. The present invention describes compounds of formula I and drug based thereon. EFFECT: improved properties of the drug based on title compounds.
| Title | Year | Author | Number |
|---|---|---|---|
| COUMARIN DERIVATIVES, USE THEREOF AS PLA INHIBITORS, AND DRUG | 1994 |
|
RU2133745C1 |
| NUCLEOSIDE PHOSPHOLIPID DERIVATIVES AND PHARMACEUTICAL COMPOSITION | 1991 |
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| 4-AMINOPYRIDINES AND A PHARMACEUTICAL COMPOSITION | 1994 |
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| DERIVATIVES OF PHOSPHONESUCCINIC ACID AND THEIR PHARMACOLOGICALLY ACCEPTABLE SALTS AND COMPOSITION BASED ON THEREOF | 1992 |
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| PROCESS FOR PREPARING DERIVATIVES OF PHENOXYALKYLCARBOXYLIC ACID, THEIR SALTS, ESTERS AND AMIDES | 0 |
|
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| PROCESS FOR PREPARING DERIVATIVES OF PHENOXYALKYLCARBOXYLIC ACID AS WELL AS THEIR SODIUM SALTS, ESTERS AND AMIDES | 0 |
|
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| METHOD OF PRODUCING OXIMES OF PYRUVIC ACID,OR THEIR SALTS OR AMIDES | 0 |
|
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| METHOD OF SYNTHESIS OF 3- (HEXADECANESULFONYL- OR SULFINYL -2- METHOXYMETHYLPROPYL) -(2- TRIMETHYLAMMONIO-ETHYL) -PH- OSPHATE, THEIR STEREOISOMERS OR PHARMACOLOGICALLY ACCEPTIBLE SALTS | 1990 |
|
RU2035466C1 |
| PROCESS FOR PREPARING DERIVATIVES OF AMINOPROPANOL OR THEIR SALTS | 0 |
|
SU1041033A3 |
