7β--[(Z)-2-(2-AMINO-4-THIAZOLYL)-2-HYDROXYIMINOACETAMIDO]-3- -(1,2,3-TRIAZOLE-4-YL)-THIOMETHYLTHIO-3-CEPHEM-4-CARBOXYLIC ACID HYDROCHLORIDE, ITS CRYSTAL HYDRATE AND METHOD OF THEIR SYNTHESIS Russian patent published in 1998 - IPC

Abstract RU 2118959 C1

FIELD: organic chemistry and technology, antibiotics. SUBSTANCE: invention proposes 7β--[(Z)-2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido] -3- -(1,2,3-triazole-4-yl)-thiomethylthio-3-cephem-4-carboxylic acid hydrochloride and its crystal hydrates that show strong antibiotic activity and pharmaceutical stability and can be used as active components of clinically useful antibiotic compositions and methods of their synthesis. EFFECT: improved method of synthesis. 6 cl, 2 tbl, 16 ex, 2 dwg

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RU 2 118 959 C1

Authors

Khisanori Takakhasi

Jutaka Ide

Dates

1998-09-20—Published

1993-07-30—Filed