FIELD: pharmaceutical chemistry. SUBSTANCE: antiestrogen has general formula I: 
(I), where R1 and R2 are independently hydrogen atom, methyl, -CO-C1-C6-alkyl or -CO-Ar (Ar is optionally substituted phenyl, pyrrolydino or piperidine group, or its pharmaceutically acceptable salts. EFFECT: preserved genital function of patient and prevented development of osteoporosis. 4 cl, 5 ex
