METHOD OF SYNTHESIS OF 1-(E-ALKENYL)-1,1-DIETHYLALANES Russian patent published in 2000 - IPC

FIELD: organic chemistry and chemical technology. SUBSTANCE: invention relates to method of synthesis of the novel 1-(E-alkenyl)-1,1-diethylalanes of the formula (I) where R is Ph, C₃H₇ or C₄H₉ that involves interaction of triethylaluminium (AlEt₃) with disubstituted acetylenes of the general formula R-≡-R where R is C₃H₇, C₄H₉, Ph in the presence of titanocene dichloride Cp₂TiCl₂ as catalyst and taken in the mole ratio = (15-25) : 10 : (0.3-0.6), respectively, at the room temperature and stirring for 8-12 h. The yield of the end product is 73-92%. Proposed method ensures to synthesize individual 1-(E-alkenyl)-1,1-diethylalanes that can be used in fine organic synthesis, in part, in synthesis of Z-olefins that use used in synthesis of biologically active compounds. EFFECT: improved method of synthesis. 1 tbl