FIELD: various industries. SUBSTANCE: described is method of preparing 1,4-diazabicyclo (2,2,2)octane. Compound is prepared by heat treatment of diethanol amine in the presence of mono-or dibasic carboxylic acids. Mixture is heated, fractions are distilled off to 245 C, and fraction of higher than 245 c is treated with alkali and rectified on column in the presence of toluene at temperatures from 130 to 240 C to isolate desired product with yield of 75%. EFFECT: simplified process and increased yield of the desired product. 2 ex
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Authors
Dates
2000-12-20—Published
1999-03-29—Filed