FIELD: medicine, pharmacy. SUBSTANCE: invention proposes antibody-base medicinal agent comprising activated form of polyclonal or natural antibodies raised to histamine taken in small or supersmall doses and prepared by multiple successive dilution and external effect being mainly by homeopathic technology. Invention relates also to method of treatment of allergic and pseudoallergic responses using activated form of antibodies raised to histamine taken in small or supersmall doses in mixture of different, mainly in hundredth homeopathic dilutions. Invention provides development of effective preparation used for treatment of allergic and pseudoallergic responses without adverse effects and can be used for treatment and prophylaxis of allergic and pseudoallergic responses. EFFECT: enhanced effectiveness and valuable medicinal properties of agent, improved method of treatment. 1 tbl, 9 ex
