FIELD: medicine, rheumatology. SUBSTANCE: one should intravenously inject metotrexate at the dosage of 10 mg weekly along with prospidine 200-300 mg weekly, moreover, the latter should be introduced by drops. The method provides earlier and pronounced therapeutic effect at decreased number of complications in case of immunosuppressive therapy. EFFECT: higher efficiency of therapy. 2 ex, 6 tbl
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