ANTIHELMINTHIC PREPARATION FOR TREATING ANIMALS AND METHOD FOR ITS OBTAINING Russian patent published in 2003 - IPC

FIELD: veterinary science. SUBSTANCE: the suggested innovation deals with treating animals by using antihelminthic preparations. Antihelminthic preparation contains, weight%: 1.4-bis(tricholomethyl)benzene 97- 99%, mixture of sodium alkylbenzenesulfonates of general formula C_nH_2n-1C₆H₄SO₃Na , where n= 10-14 - 7 0,5-1,5, mixture of polyglycerols of general formula HOCH₂CHOHCH₂O(CH₂CHOHCH₂O)_nH, where n=1-3 0.5- 1.5. Method for obtaining the above-mentioned antihelminthic preparation deals with recrystallization of 1.4-bis(trichloromethyl)benzene out of mixture of benzene hydrocarbons of C₇-C₉ fraction, mixture of sodium alkylbenzenesulfonates of general formula C_nH_2n-1C₆H₄SO₃Ma, where n=10-14 at the presence of mixture of polyglycerols of general formula HOCH₂CHOHCH₂O(CH₂CHOHCH₂O_nH,, where n=1-3 taken at ratio to sodium alkylbenzenesulfonates being 1-3:1-3 against weight. Moreover, the mixture of all mentioned substances used to fulfill recrystallization should be preliminary dried due to azeotropic evaporation of water and part of benzene hydrocarbons. Application of the suggested preparation enables to increase antihelminthic efficiency at cattle fascioliasis: at the dosage of 0.2 g/kg by 98.7-100% and in sheep at the dosage of 0.140 g/kg by 100%. Advantages of the method are: accelerated recrystallization process of 1.4-bis(trichloromethyl)benzene, increase yield of target product, decreased quantity of waste products and more simplified technological scheme. EFFECT: higher efficiency of therapy. 2 cl, 6 tbl