ANTI-TUBERCULOSIS PREPARATION Russian patent published in 2003 - IPC

FIELD: medicine, phthisiology, pharmacy. SUBSTANCE: invention relates to medicinal agents used in treatment of tuberculosis patients. An anti-tuberculosis preparation represents a pharmaceutical composition containing isoniazide (isonicotinic acid hydrazide) taken in the dose 5-15 mg/kg; 2,4-dioxo-5-fluoropyrimidine (fluorouracil) taken in the dose 0.1-2.5 mg/kg and pharmaceutically acceptable carrier. Ratio of isoniazide to fluorouracil can be equal (2:1)-(150:1) by the weight. Composition can be made as solution and administrated by intramuscular or intravenous route. Preparation shows high an anti-tuberculosis activity with combination of reduced toxic effect. EFFECT: enhanced and valuable medicinal properties of preparation. 4 cl, 2 tbl