FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to methods for preparing 3-cyano-2,4-dihalogen-5-fluorobenzoic acids of the formula (I) 
wherein X and Y mean independently each of other halogen and that are intermediate compounds used for preparing effective antibacterial substances. Method involves hydrolytic cleavage of 3-cyano-2,4-dihalogen-5-fluorobenzoic acid amide (II) 
or 3-cyano-2,4-dihalogen-5-fluorobenzoic acid ester of the formula (III) 
wherein X and Y have above indicated values and R means alkyl with 1-4 carbon atoms that can be optionally substituted in the presence of acid and water at temperature 0-220 C. Invention relates also to novel compounds of the formula (Ia) 
wherein X and Y mean independently each of other halogen atom; Z means group CN, 
or COOR wherein R means alkyl with 1-4 carbon atoms that can be optionally substituted; in the case Z CN X and Y mean nonsimilar residues taken among group consisting of fluorine and chlorine atom, or both residues mean chlorine atom; in the case Z - COOR R doesn't mean methyl and each radical X and Y doesn't mean fluorine atom. These compounds are intermediate substances used for preparing compounds of the formula (I). Methods can be used for preparing compounds of the formula (I) in large-scale industrial production. EFFECT: improved preparing method. 4 cl, 9 dwg, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITION ELICITING ANTI-BACTERIAL ACTIVITY | 1997 |
|
RU2173318C2 |
| CARBANILIDES AND AGENT FOR CONTROL OF INSECTS AND PATHOGENIC FUNGI BASED ON THEREOF | 1997 |
|
RU2194704C2 |
| DERIVATIVES OF N-SULFONYLIMIDAZOLE AND THEIR ACID-ADDITIVE SALTS AND FUNGICIDE AGENT BASED ON THEREOF | 1997 |
|
RU2171806C2 |
| METHOD AND INTERMEDIATES COMPOUNDS FOR SYNTHESIS OF SIMPLE HYDROXYLAMINE ETHERS AND THEIR SALTS | 1993 |
|
RU2119911C1 |
| ISOTHIAZOLE CARBOXYLIC ACID AMIDES AND METHOD FOR THEIR PREPARING | 1998 |
|
RU2214403C2 |
| 2-METHOXYIMINOPHENYLACETIC ACID ORTHO-SUBSTITUTED AMIDES, METHOD OF THEIR SYNTHESIS, AGENT FOR HARMFUL FUNGI CONTROL AND INSECTOACARICIDE AGENT | 1994 |
|
RU2130924C1 |
| SUBSTITUTED ARYLKETONES | 2001 |
|
RU2299879C2 |
| METHOD OF PRODUCING DERIVATIVES OF ACRYLIC ACID | 0 |
|
SU1395139A3 |
| 2,4,5-TRISUBSTITUTED PHENYLKETOENOLES, INTERMEDIATE COMPOUNDS FOR THEIR SYNTHESIS, METHOD AND AGENT FOR CONTROL OF INSECTS AND SPIDERS BASED ON THEREOF | 1996 |
|
RU2195449C2 |
| 3-HALOGEN-3-HETARYLCARBOXYLIC ACID DERIVATIVES, AND HERBICIDAL AGENT | 1994 |
|
RU2146255C1 |
