FIELD: veterinary microbiology. SUBSTANCE: strain of bacterium Salmonella enteritidis = 22 shows morphological, cultural and enzymatic properties that are typical for genus Salnonella. By serological properties the proposed strain is agglutinated with salmonellosis monoreceptor sera 09 (1 and 5 complex) H-G. The strain is producer of endotoxin and hemolysine, it shows protein structure and nucleoitide composition of its DNA (% GC) - 53.1. It comprises plamids with molecular mass 60 mDa and is lyzed by polyvalent bacteriophage. Virulent properties: value LD50 for white mice in intraperitoneal administration is 2.4 x 106 live microbe cells. The strain is pathogenic for newborn calves and oral infection in the dose 10 billions microbe cells diarrhea is evident in 24 h and death of animal - in 2-3 day. Concentration of microbe cells in culturing the strain is 40-50 billions by optical turbidity standard GISK named after K. A. Tarasevich, protective effect against infection with virulent strains is on 5-7 day. The strain is useful for preparing vaccines against salmonellosis in animals and for preparing diagnostic preparation and hyperimmune curative sera and globulins. EFFECT: valuable biological and medicinal properties of strain. 1 ex
Title | Year | Author | Number |
---|---|---|---|
VACCINE AGAINST CHICKEN SALMONELLOSIS AND A METHOD OF PROPHYLAXIS OF CHICKEN SALMONELLOSIS | 1992 |
|
RU2030916C1 |
STRAIN OF BACTERIUM SALMONELLA DUBLIN = 19 USED FOR PREPARING VACCINE AND DIAGNOSTIC PREPARATION | 2002 |
|
RU2218176C2 |
PREPARATION FOR CONTROL OF CHICKEN SALMONOLLOSIS AND METHOD OF TREATMENT AND PREVENTIVE TREATMENT OF CHICKEN SALMONOLLOSIS | 1992 |
|
RU2026082C1 |
STRAIN OF BACTERIUM SALMONELLA TYPHIMURIUM = 14 USED FOR PREPARING VACCINES AND DIAGNOSTIC PREPARATIONS | 2002 |
|
RU2216350C2 |
VACCINE AGAINST PORCINE SALMONELLOSIS | 2003 |
|
RU2255763C2 |
VACCINE AGAINST PIG SALMONELLOSIS, METHOD OF ITS PREPARING AND A METHOD OF PIG SALMONELLOSIS PROPHYLAXIS | 1988 |
|
RU1577116C |
BACTERIUM STRAIN SALMONELLA DUBLIN USED FOR PREPARATION OF VACCINE AGAINST CALVES SALMONOLLOSIS | 1984 |
|
SU1197186A1 |
INACTIVATED EMULSION-VACCINE AGAINST SALMONELLOSIS IN CALVES | 1997 |
|
RU2154495C2 |
VACCINE INACTIVATED AGAINST SALMONELLOSIS OF DOVES AND METHOD OF ITS APPLICATION | 2008 |
|
RU2377015C1 |
METHOD TO PREVENT SALMONELLA-CAUSED ABORTION IN MARES | 2000 |
|
RU2178713C2 |
Authors
Dates
2003-12-10—Published
2002-01-18—Filed