FIELD: medicine, biology, immunology, biotechnology, immunopharmacology, fur farming. SUBSTANCE: the present method deals with applying either antiidiotypical antibodies or their F(ab)- fragments being immunochemical analogues of ("mimicrizing") main antigens of aleutian disease viruses in minks as a vaccine preparation to prevent applied viral immunodeficiency as aleutian disease. The present innovation enables to decrease sickness rate and lethality in minks by 3-4 times. EFFECT: higher efficiency of prophylaxis. 1 tbl
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