FIELD: medicine. SUBSTANCE: invention claims anti-thrombotic agents comprising humanized antibodies produced by hybridoma AjvW-2 that bind von Willebrand factor and can be used for treatment of thrombotic diseases and to method for their preparing also. Invention provides using the improved forms of humanized immunoglobulins that are not immunogenic for humans. EFFECT: improved and valuable properties of agent. 18 cl, 2 tbl, 3 dwg, 4 ex
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