FIELD: organic chemistry, heterocyclic compounds, medicine, cardiology.
SUBSTANCE: invention relates to new chemical compounds of heterocyclic row eliciting the expressed anti-calcium activity and representing derivatives of 2-H-1-benzopyrane-2-one of the general formula (I):
wherein R and R1 have values given in the invention claim. Proposed compounds can be used in medicinal practice in treatment and prophylaxis of cardiovascular diseases.
EFFECT: valuable medicinal properties of compounds.
7 tbl, 1 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| MEDICAMENT WITH PROLONGED ANTI-CALCIUM ACTIVITY IN THE FORM OF 1/10% INTRAVENOUS SOLUTION | 2004 |
|
RU2255728C1 |
| AGENT FOR TREATMENT OF PATIENT WITH HEART ISCHEMIC DISEASE | 1998 |
|
RU2155036C2 |
| ANTIARRHYTHMIC MEDICATION BASED ON 4-METHYL-7,7'-ETHYLENEDIOXY-2H-1-DIBENZOPYRAN-2,2'-DIONE | 2010 |
|
RU2427368C1 |
| ANTIARRHYTHMIC DRUG BASED ON HYBRID MOLECULES OF AMLODIPINE WITH (7-METHOXICUMARIN-4-YL)ACETIC ACID | 2018 |
|
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| METHOD OF PREPARING DIUMANCAL-FORTE TABLETS IN DOSE 0,01 G | 2000 |
|
RU2187303C2 |
| ANCARDIN-RETARD AS AGENT WITH PROLONGED ANTI-CALCIUM EFFECT | 2002 |
|
RU2219927C1 |
| ANTICOAGULANT AGENT OF INDIRECT ACTION ON BASIS OF DIUMANCAL | 2018 |
|
RU2671983C9 |
| THE SUBSTANCE POSSESSING AN ANTICALCIUM ACTIVITY | 0 |
|
SU1836087A3 |
| 1-[ω-(N,N-SUBSTITUTED AMINO)-ALKYL]-2-(2-ACYLETHENYL)- -PYRROLES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS SHOWING ANTIARRHYTHMIC AND ANTIISCHEMIC ACTIVITY | 1993 |
|
RU2088573C1 |
| ANTICOAGULANT AGENT OF INDIRECTLY ACTION BASED ON NEW HYBRID MOLECULE OF WARFARIN WITH ESSENTIAL ACID | 2018 |
|
RU2677647C1 |
