FIELD: biotechnology, food processing industry, medicine.
SUBSTANCE: strain Bifidobacterium bifidum is obtained by sequential cycles of lyophilic drying and reducing on thioglycol cultural medium (50 cycles). Clones with excellent antioxidant activity have been selected according to maximum accumulation of bifidus-bacteria biomass in sterile defatted milk not less than lg 9 after cultivation for 16 h. Strain has superoxide dismutase activity not less than 19.7 unit/mg of microbial protein mass. Strain Bifidobacterium bifidum can effectively growth in cultivation media and accumulate necessary titer of viable bacteria, has high acid-forming activity, antagonistic action against pathogenic and conditional pathogenic microflora, and excellent antioxidantaction. Culture has marked probiotic action cased by its superoxide dismutase activity. Strain is useful in preparation of functional foodstuff, bioactive supplement, cosmetic and toiletry agents.
EFFECT: bifidus-bacterium strain for manufacturing of products with excellent probiotic and healthy effect.
2 tbl, 5 ex
