FIELD: medicine, pharmacology, pharmacy.
SUBSTANCE: invention relates to a novel granulated formulaton of emetine hydrochloride used in prophylaxis and treatment of alcoholism. The formulation comprises 70-90% of emetine hydrochloride, polyvinylpyrrolidone and eudragite, a tabletted or capsulated medicinal formulation based on thereof. Also, invention relates to a method for preparing the indicated granulate. Invention provides delivery of emetine hydrochloride in intestine and suppression of the emetic effect.
EFFECT: improved preparing method, valuable medicinal properties of granulate.
4 cl, 6 tbl, 32 ex
| Title | Year | Author | Number |
|---|---|---|---|
| ANTIOXIDANT USED IN PROPHYLAXIS IF DISEASES ASSOCIATED WITH OXIDATIVE STRESS, METHOD FOR ITS PREPARING, GRANULATE CONTAINING THEREOF, AND TABLETTED OR CAPSULATED FORMULATED BASED ON THEREOF | 2006 |
|
RU2309740C1 |
| PHARMACEUTICAL COMPOSITION, POSSESSING GABA-ERGIC ACTIVITY | 2014 |
|
RU2550960C1 |
| PHARMACEUTICAL COMPOSITION POSSESSING GABA ACTIVITY | 2012 |
|
RU2496496C1 |
| PROPHYLACTIC AND GENERAL TONIC AGENT | 1997 |
|
RU2121360C1 |
| METHOD OF REDUCING PATHOLOGIC ATTRACTION TO ALCOHOL IN POST ABSTINENT PERIOD | 2008 |
|
RU2397761C2 |
| PHARMACEUTICAL COMPOSITION POSSESSING PROPERTIES OF VITAMIN D RECEPTOR ACTIVATION | 2014 |
|
RU2571503C1 |
| PROPHYLACTIC AND GENERAL RESTORATIVE AGENT (ITS VARIANTS) | 1996 |
|
RU2100019C1 |
| WIDE-SPECTRUM PROPHYLACTIC AND GENERAL HEALTH-IMPROVING REMEDIES | 1999 |
|
RU2145228C1 |
| METHOD OF TREATMENT OF ALCOHOLISM | 2005 |
|
RU2323727C2 |
| PROLONGED ANTIHYPERTENSION PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING IT | 2012 |
|
RU2543637C2 |
