FIELD: medicine, microbiology, immunology.
SUBSTANCE: claimed method includes providing of serum from rabbits hyperimmunized with inactivated and then with living pertussis microbes. Then using affine sorbent based on aluminum hydroxide gel anti-pertussis antibodies are isolated from serum followed by additional purification by exhaustive adsorption with parapertussis microbes adsorbed on aluminum hydroxide gel; mixed with staphylococci suspension containing A protein, precipitated vy centrifugation, resuspended in buffered physiological saline of pH 7.2-7.4 in form of 2 % suspension and used as diagnosis reagent in coagglutination reaction.
EFFECT: method of increased sensitivity.
1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF DIAGNOSIS OF PERTUSSIS INFECTION | 0 |
|
SU1255929A1 |
| METHOD FOR ESTIMATION OF EFFECIENCY OF VACCINATION AGAINST PERTUSSIS, DIPHTHERIA AND TETANUS | 2016 |
|
RU2626679C1 |
| METHOD OF SERUM DIAGNOSTICS OF PERTUSSIS | 2009 |
|
RU2424530C1 |
| MANUFACTURE METHOD OF BLOOD SERUM STANDARD POSITIVE PANEL FOR QUALITY CONTROL OF IMMUNOENZYMOMETRIC TEST SYSTEMS DESIGNED FOR DETECTION OF VIRUS-SPECIFIC ANTIBODIES TO VIRAL RESPIRATORY INFECTIONS IN BIOLOGICAL LIQUIDS OF BOVINE ANIMALS | 2008 |
|
RU2392331C2 |
| 0 |
|
SU1363569A1 | |
| METHOD FOR EXPRESS-DIAGNOSIS OF WHOOPING COUGH | 2003 |
|
RU2247388C1 |
| STRAIN OF HYBRIDOUS CULTURED MAMMALIAN CELLS MUS MUSCULUS L - PRODUCER OF MONOCLONAL ANTIBODIES TO BACTERIA OF BRUCELLA GENUS | 0 |
|
SU1752764A1 |
| METHOD OF PREPARING ANTIBODY DIAGNOSTICUM OF SALMONELLA | 0 |
|
SU1082401A1 |
| METHOD OF CLOSTRIDIUM PERFRINGENS TOXINS INDICATION | 0 |
|
SU1745768A1 |
| MIXED VACCINE FOR IMMUNOPROPHYLAXIS OF WHOOPING COUGH, DIPHTHERIA, TETANUS AND VIRAL HEPATITIS B AND D | 2003 |
|
RU2233673C1 |
