METHOD OF COMPLEX EVALUATION OF MORPHOTIPIC SIGNS ASSOCIATED WITH CONNECTIVE TISSUE DYSPLASIA Russian patent published in 2008 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: perform a complex evaluation of the morphotipic signs associated with a connective tissue dysplasia, by revealing and the quantitative characteristic of set of such signs. Choose only the signs giving in to objective measurement and characterised by quantity indicators for evaluation. As an evaluation of degree of expression of each sign accept size of a relative deviation of a corresponding quantity indicator at this indicator surveyed from average norm, expressed in sizes of a root-mean-square deviation. The obtained estimations use for calculation of an integrated displasia indicator (IDI) under the formula: IDI=-CI+PE+GF+ChI+SF+TB+WT+FL-HM+FF+UJ+KJ, where CI - an estimation of size of the Cegle index, PE - estimation of size of Penier index, GF - estimation of size of an indicator of the general flexibility, ChI - an estimation of size of Chizhin index, SF - an estimation of size of height of a skin fold on a hand, TB a - estimation of size of an indicator under the test of the big finger, then WT-estimation of size of an indicator under the wrist test, FL - an estimation of size of the relation of length of the third finger of a hand to length of a hand, HM - an estimation of size of degree of mobility in hand joints, FF - an estimation of size of an angle of an extension in a metacarpophalangeal joint of the fifth finger, UJ - an estimation of size of an angle of an extension in an ulnar joint, KJ - an estimation of size of an angle of an extension in a knee joint. At IDI value less than 1.8, estimate expression of morphotopic signs, associated with dysplasia of a connective tissue as low (a norm version), from 1.9 to 5.9 - as average with probability of presence (or possible development) separate clinical IDI implications, and above 5.9 - as high with probability of presence of the developed IDI syndrome.

EFFECT: allows to raise objectivity and accuracy of an estimation of morphotipic signs, associated with IDI, and also to make preliminary diagnostics of IDI syndrome.

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