SUBSTITUTED 2-THIOCARBAMOYL-3-PHENYL-3,3a,4,5,6,7-HEXAHYDRO-2N-INDAZOLES, METHOD OF PRODUCING SAID COMPOUNDS (VERSIONS) AND FUNGICIDE COMPOSITION BASED ON SAID COMPOUNDS Russian patent published in 2009 - IPC C07D231/56 A01N43/56 

FIELD: chemistry.

SUBSTANCE: invention relates to new substituted 2-thiocarbamoyl-3-phenyl-3,3a,4,5,6,7-hexahydro-2N-indazoles with general formula I

, where R1=CH₃, R2=H, CH₃, R1+R2=(CH₂)_m, m=2-5; X=C_kH_2k+1 k=1-4, Hal, NO₂, C_kF_2k+1 n=1-5; R3=CH₃, Alk, Ar, and method of producing them, the first of which involves condensation of 2-arylidenecyclohexanones II with thiosemicarbazides III in aliphatic alcohol in the presence of acid as catalyst while heating (mainly 3,3a-cis-2-thiocarbamoyl-3-phenyl-3,3a,4,5,6,7-hexahydro-2N-indazoles of formula I are obtained using this method); in the second method, through condensation of 2-arylidenecyclohexanones II with hydrazine hydrate while boiling in aliphatic alcohol, intermediate N-unsubstituted hexahydroindazoles IV are obtained, which are acylated with alkyl- or arylisothiocyanates in an inert solvent in the presence of a base catalyst at room temperature (mainly 3,3a-trans-2-thiocarbamoyl-3-phenyl-3,3a,4,5,6,7-hexahydro-2N-indazoles of formula I are obtained using this method).

EFFECT: invention relates to a fungicide composition which contains substituted 2-thiocarbamoyl-3-phenyl-3,3a,4,5,6,7-hexahydro-2N-indazoles with general formula I, for example, 7-methyl- or 7,7-dimethyl-3-(4-chlorobenzylidene)-3,3a,4,5,6,7-hexahydro-2N-indazoles, which exhibits fungitoxicity higher than standard triadimefon.

4 cl, 5 tbl, 5 ex