METHOD FOR NORMALISING FUNCTIONAL REACTIVITY OF CARDIOVASCULAR SYSTEM AMONG PATIENTS SUFFERING FROM ARTERIAL HYPERTENSION AND ABDOMINAL OBESITY Russian patent published in 2010 - IPC A61K31/4155 A61P9/12 A61H1/00 

Abstract RU 2388470 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to cardiology, and concerns normalising functional reactivity of cardiovascular system (CVS) at arterial hypertension and abdominal obesity. To that end, the state of CVS functional reactivity at psychoemotional stress is assessed by recording systolic, diastolic and average dynamic blood pressure (BP av.dyn) and heart rate (HR). These data serve as the basis for determining functional reactivity index (FRI) prior to and after the stress, according to the following formula: FRI = (BP av.dyn. × heat rate)/100 (conv. un.). If FRI value after stress rises by more than 20 conventional units, complex therapy is implemented including individual hypocaloric diet calculated by a formula considering sex and age, sensibly graded static and dynamic physical exercise as well as administration of losartane in a dose of 50 mg once a day, in the morning, over at least 4 months.

EFFECT: complex of drug and non-drug treatment combined with empirically chosen course duration ensures normalisation of CVS functional reactivity among the specified group of patients due to potentiation of certain components of the therapeutic complex.

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RU 2 388 470 C1

Authors

Simonenko Vladimir Borisovich

Medvedev Il'Ja Nikolaevich

Zavalishina Svetlana Jur'Evna

Bespartochnyj Boris Dmitrievich

Dates

2010-05-10Published

2009-04-13Filed