FIELD: medicine.
SUBSTANCE: method is proposed for preventing or slowing down development of atherosclerosis. It involves administration of molsidomine or a pharmaceutically acceptable salt thereof in the form of solid peroral composition with prolonged release of the active substance, effective for 24 hours and containing 14 to 24 mg of molsidomine. The composition is to be administered for at least 6 months.
EFFECT: method significantly decreases level of circulating ICAM-1s (an anti-inflammatory marker of endothelium dysfunction and therapeutic target at atherosclerosis pathological conditions) which play an important role in emergence and development of atherosclerosis.
6 cl, 2 dwg, 2 tbl
