METHOD FOR PREVENTION OF CANCEROGENIC ACTION OF METHYLNITROSOUREA IN EXPERIMENTAL ANIMALS Russian patent published in 2011 - IPC A61K31/427 A61K31/17 A61P35/00 

FIELD: medicine.

SUBSTANCE: method includes fivefold introduction of methylnitrosourea in dosage 2.5 mg per a rat in 0.2 ml of water for injections over one week for 1.5 months in tissue of the same breast at a base of the left front legs. As an anticarcinogen, meloxicam is added to forage in dosage 1.8 mg/kg of body weight 2 times a week for 9 months.

EFFECT: reduced cancerogenic effect of methylnitrosourea due to inhibition of cyclooxygenase-2 in tumour tissue, tumour angiogenesis, decreased number of side effects.

2 tbl, 4 dwg, 1 ex