METHOD OF LOCAL CHEMOTHERAPY OF HEPATIC METASTASES Russian patent published in 2011 - IPC A61B18/04 A61K31/513 A61P35/00 

Abstract RU 2411018 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to oncology, and can be used in chemotherapy of hepatic metastases. The method involves radio-frequency thermal ablation followed by treating hepatic tissue within a necrosis region with an aqueous solution of 5-fluorouracil. The solution contains 5-fluorouracil 0.087 wt %, water for injections 1.754 wt %, low-molecular polyethylene 67.114 wt %, emulsifier T-2 16.778 wt %, microcrystalline gelatine 6.717 wt %, oil olive 7.550 wt %.

EFFECT: invention provides prevention of general toxic effect and malignant cell enlargement ensured by prolonged release 5-fluorouracil for 4 weeks.

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Authors

Gantsev Shamil' Khanafievich

Ishmuratova Renata Shamil'Evna

Gantsev Kamil' Shamil'Evich

Likhoded Vitalij Alekseevich

Zajnullin Feliks Shamil'Evich

Ajupov Rustem Talgatovich

Brazhenko Mikhail Aleksandrovich

Sulejmanov Nail' Maratovich

Atnabaev Roman Danisovich

Dates

2011-02-10Published

2009-12-22Filed