TRANS-CLOMIPHENE DOSING REGIMEN Russian patent published in 2011 - IPC A61K31/138 A61P15/00 A61P3/06 A61P35/00 

Abstract RU 2413508 C2

FIELD: medicine.

SUBSTANCE: offered is application of a composition substantially consisting of trans-clomiphene or its pharmaceutically acceptable salt for preparing a drug to be introduced in a male patient in a single dose every 3-30 days for treating hypogonadism, lipodystrophy, benign prostatic hypertrophy or prostate cancer (versions). One of side effect of exogenous testosterone, namely decreased biosynthesis level of follicle-stimulating hormone causing reduced sperm formation is compensated. Contrariwise, the product is applied in treating a disorder associated with male hypogonadism and related disturbances, including reduced muscle bulk, body physical capacity limitation, decreased bone density, decreased libido, decreased potency, reduced benign prostatic hyperplasia and infertility.

EFFECT: product increases persistently total testosterone level to a normal range with no abnormal high peaks.

18 cl, 7 dwg, 3 ex

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RU 2 413 508 C2

Authors

Podolski Dzhozef

Dates

2011-03-10Published

2006-03-17Filed