METHOD OF TREATING ULCEROUS DISEASE OF DUODENUM IN CHILDREN, ASSOCIATED WITH FUNGUS OF GENUS Candida Russian patent published in 2011 - IPC A61K31/4196 A61P1/04 

Abstract RU 2416405 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to gastroenterology, and can be applied for treatment of duodenum ulcerous disease in children (UDD). For this purpose in complex therapy included is fluconazole (diflucan). Doses and regime of fluconazole introduction are determined depending on the level of circulating candidal antigen in blood serum. At high level of candidal antigenemia (10-4/10-5 mg/ml) medication is administered in form of intravenous injections in dose 5 mg/kg 1 time per day during 3 days, then 7 days inside in dose 3 mg/kg, and after that 1 time per week once during a month in dose 150 mg. At moderate level of candidal antigenemia (10-6 /10-7 mg/ml) flucanazole is administered inside by 5 mg/kg during 7 days, then 1 time per week in dose 150 mg during a month. At low level of candidal antigen in blood serum (10-8 /10-9 mg/ml) medication is taken inside in dose of 3 mg/kg during 7 days, then once in dose 150 mg.

EFFECT: method makes it possible to reduce level of circulating candidal antigen in blood serum of patients with any level of candidal antigenemia.

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RU 2 416 405 C1

Authors

Malanicheva Tat'Jana Gennad'Evna

Narykov Rinat Khamidovich

Ziatdinova Nelli Valentinovna

Novozhilova Alla Alekseevna

Sofronov Valerij Viktorovich

Dates

2011-04-20Published

2009-12-08Filed