FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to field of organic chemistry, medicine and veterinary, in particular to method of obtaining medication of sodium salt of 5-amino-2,3-dihydro-1,4-phthalazinedione by reduction of 3-nitrophthalic acid in alkaline medium in presence of nickel catalyst, interaction of obtained 3-aminophthalic acid with hydrazinhydrate in medium of acidic acid with further processing with metal zinc in alkaline medium at heating and sodium hydroxide in ethyl alcohol medium at heating.
EFFECT: method makes it possible to increase output and quality of sodium salt of 5-amino-2,3-dihydro-1,4-phthalazinedione, simplify process of obtaining and reduce cost of target product.
4 dwg
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