ANTIBACTERIAL AND ANTIMYCOTIC COMPOSITION OF WIDE SPECTRUM OF ACTION OF PHOSPHONIUM SALTS AND SUBSTITUTED BENZOFUROXANE Russian patent published in 2012 - IPC A61K31/14 

Abstract RU 2452477 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention preferentially refers to veterinary science and medicine, namely antibacterial and antimycotic (fungicidal) compositions applicable as a disinfectant and an anti-infectious agent of wide spectrum of action in veterinary science, medicine and various areas of national economy. The invention discloses a new number of 10 pharmaceutical combined drug preparations wherein each preparation consists of quaternary phosphonium halide on the basis of tributyl- and triphenyphosphines with higher haloid alkyls and 5,7-dichloro-4,6-nitrobenzofuroxane as active ingredients in equimolar ratio.

EFFECT: invention provides a non-toxic composition (LD50 2500 mg/kg) which shows very high efficacy in low (1 %) therapeutic doses.

2 tbl, 10 ex

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Authors

Galkina Irina Vasil'Evna

Pozdeev Oskar Kimovich

Shulaeva Marina Petrovna

Egorova Svetlana Nikolaevna

Jusupova Luiza Magdanurovna

Tudrij Elena Vadimovna

Bakhtijarova Julija Valer'Evna

Morozova Lidija Grigor'Evna

Kipenskaja Larisa Viktorovna

Kljushina Ljudmila Valentinovna

Zakirjanova Faina Nikolaevna

Galkin Vladimir Ivanovich

Dates

2012-06-10Published

2011-01-12Filed