FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to new indole compounds of formula:
wherein A means 5-member heteroaryl or heterocyclyl each of which has 1 to 3 heteroatoms specified in N, O and S, R1 means R5 -X-B-X'-, R2 means -(CR8 R9 )p-Y-R7, R3 means hydrogen, C1-C6-alkyl or -(CH2)q-C3-C6-cycloalkyl, R4 means C3-C6-cycloalkyl (the other radical values are presented in cl.1 of the patent claim), their pharmaceutically acceptable salts or isomers which may be used for preventing or treating cell necrosis and necrosis-related diseases.
EFFECT: preparing the compounds to be used for preventing or treating cell necrosis and necrosis-related diseases.
34 cl, 2 tbl, 263 ex
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