ANTI-CANCER AGENTS WITH BENZOPHENANTHRIDINE STRUCTURE AND PREPARATIONS CONTAINING THEM Russian patent published in 2013 - IPC A61K31/473 A61K31/661 A61K31/728 C07D221/10 C07F9/10 C08B37/08 A61P35/00 

Abstract RU 2492862 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: there are presented: using benzophenanthridine alkaloid salts for preparing therapeutic agents for treating tumours, wherein the alkaloid salt is found in the form luteic, phosphatidic or hyaluronic acid, the benzophenanthridine alkaloid salt with phosphatidic acid or hyaluronic acid, and a based pharmaceutical composition for treating tumours.

EFFECT: what is shown is cytotoxic activity of the sanguinarine salts according to the invention at least twice increased in all studied tumour cell lines in relation to the chloride salt; it is suggested to be caused by higher absorption by the tumour cells.

12 cl, 8 ex

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RU 2 492 862 C2

Authors

Bombardelli Ehtsio

Fontana Gabriele

Moratstsoni Paolo

Riva Antonella

Dates

2013-09-20Published

2009-02-16Filed