FIELD: biotechnologies.
SUBSTANCE: invention refers to a compound having general formula (I),
where: m and n are independent integer numbers of 1 to 6; each of X1-X3 and Y1-Y3 is O; each of R1-R3 is independently chosen from a group consisting of hydrogen or alkyl; and R is O-(CH2)x-C(-O)NR'-(CH2)y-NHR'. Besides, x and y are independent integer numbers of 1 to 6; and R' is chosen from the group consisting of hydrogen and alkyl. In addition, an antibody containing an antigen recognition area, use of the compound, pharmaceutical composition, use of the antibody, method for MMP-2 or MMP-9 activity inhibition in a sample and a composition for determining MMP-2 or MMP-9 are proposed.
EFFECT: invention allows obtaining compounds that are able to inhibit MMP-2 or MMP-9 activity.
11 cl, 16 dwg, 4 tbl, 11 ex
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Authors
Dates
2014-01-10—Published
2008-02-21—Filed