Show metadata Hide metadata

(19)

(11)

2 507 198

(13)

(51)

IPC

C07D239/88(2006-01-01)

A61K31/517(2006-01-01)

A61P25/28(2006-01-01)

A61P9/10(2006-01-01)

(21) (22)

Application

2012138665/04, 2012-09-10

(24)

Start date

2012-09-10

(22)

Actual filing date

2012-09-10

(45)

Published

2014-02-20

(72)

Inventor

Petrov Vladimir IvanovichTjurenkov Ivan NikolaevichOzerov Aleksandr Aleksandrovich

(73)

Holder

Petrov Vladimir IvanovichTjurenkov Ivan NikolaevichOzerov Aleksandr Aleksandrovich

QUINAZOLINE DERIVATIVES, POSSESSING NOOTROPIC AND ANTIHYPOXIC ACTIVITY Russian patent published in 2014 - IPC C07D239/88 A61K31/517 A61P25/28 A61P9/10

Abstract RU 2507198 C1

FIELD: chemistry.

SUBSTANCE: invention relates to novel medication, possessing nootropic and antihypoxic activity, which represents arylamides of 2-[4-oxo-3(4H)quinazolinyl]acetic acid of general formula where R=o-CH₃, n-CH₃ or 2,3-phenylene. Compounds demonstrated original spectrum of psychotropic action, exceeding in complex of useful properties medications of different pharmacological groups - piracetam, phenibut, phenotropil, mexidol, on experimental models in vivo.

EFFECT: compounds can be widely applied in treatment of patients with organic affection of brain.

3 tbl, 5 ex

Similar patents RU2507198C1

Title	Year	Author	Number
QUINAZOLINE DERIVATIVES, POSSESSING ANTIDEPRESSANT, ANXIOLYTIC AND NOOTROPIC ACTIVITY	2012	Petrov Vladimir Ivanovich Tjurenkov Ivan Nikolaevich Ozerov Aleksandr Aleksandrovich	RU2507199C1
9-[2-(4-ISOPROPYLPHENOXY)ETHYL]ADENINE POSSESSING ANTIDEPRESSANT AND STRESS-RELIEVING ACTION	2013	Petrov Vladimir Ivanovich Tjurenkov Ivan Nikolaevich Ozerov Aleksandr Aleksandrovich	RU2529817C1
4-[(4-ACETOXYBENZOYL)AMINO]BUTYRATE OF LITHIUM, HAVING CEREBROPROTECTIVE ACTION	2015	Brel Anatolij Kuzmich Tyurenkov Ivan Nikolaevich Lisina Svetlana Viktorovna Budaeva Yuliya Nikolaevna Volotova Elena Vladimirovna Kurkin Denis Vladimirovich Bakulin Dmitrij Aleksandrovich	RU2617233C2
DISODIUM SALT OF 3-HYDROXYHIPPURIC ACID, HAVING ANTIHYPOXIC AND CEREBROPROTECTIVE ACTION	2014	Brel' Anatolij Kuz'Mich Tjurenkov Ivan Nikolaevich Lisina Svetlana Viktorovna Budaeva Julija Nikolaevna Rodina Natal'Ja Valentinovna Volotova Elena Vladimirovna Kurkin Denis Vladimirovich Bakulin Dmitrij Aleksandrovich	RU2559875C1
MEDICATION POSSESSING ANTIDEPRESSIVE, ANXIOLYTIC AND NOOTROPIC ACTION	2010	Berestovitskaja Valentina Mikhajlovna Vasil'Eva Ol'Ga Sergeevna Ostrogljadov Evgenij Sergeevich Petrov Vladimir Ivanovich Tjurenkov Ivan Nikolaevich Bagmetova Viktorija Vladimirovna	RU2437659C1
AGENT ELICITING ANTI-ISCHEMIC, HYPOTENSIVE, ANTI- -ARRHYTHMIC AND NOOTROPIC ACTIVITY	2002	Berestovitskaja V.M. Vasil'Eva O.S. Novikov B.M. Usik N.V. Zobacheva M.M. Tjurenkov I.N. Perfilova V.N. Borodkina L.E.	RU2216322C1
DERIVATIVE OF 3-HYDROXYPYRIDINE WITH ANXIOLYTIC AND NOOTROPIC EFFECT	2017	Bogomolova Olga Alekseevna Demidova Marina Aleksandrovna Skachilova Sofiya Yakovlevna	RU2664453C1
POTASSIUM N-(4-ACETOXYBENZOYL)GLYCINATE POSSESSING CEREBROPROTECTIVE ACTIVITY	2014	Brel' Anatolij Kuz'Mich Tjurenkov Ivan Nikolaevich Lisina Svetlana Viktorovna Budaeva Julija Nikolaevna Rodina Natal'Ja Valentinovna Volotova Elena Vladimirovna Kurkin Denis Vladimirovich Bakulin Dmitrij Aleksandrovich	RU2556637C1
DISODIUM SALT OF SALICYLURIC ACID, POSSESSING CEREBROPROTECTIVE ACTIVITY	2014	Brel' Anatolij Kuz'Mich Tjurenkov Ivan Nikolaevich Lisina Svetlana Viktorovna Budaeva Julija Nikolaevna Rodina Natal'Ja Valentinovna Volotova Elena Vladimirovna Kurkin Denis Vladimirovich Bakulin Dmitrij Aleksandrovich	RU2570644C1
PHENYLHYDRAZIDE (4-PHENYL-2-PYRROLIDON-1-YL)-ACETIC ACID, HAVING NOOTROPIC, ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY	2010	Berestovitskaja Valentina Mikhajlovna Vasil'Eva Ol'Ga Sergeevna Ostrogljadov Evgenij Sergeevich Petrov Vladimir Ivanovich Tjurenkov Ivan Nikolaevich Bagmetova Viktorija Vladimirovna	RU2440981C1

RU 2 507 198 C1

Authors

Petrov Vladimir Ivanovich

Tjurenkov Ivan Nikolaevich

Ozerov Aleksandr Aleksandrovich

Dates

2014-02-20—Published

2012-09-10—Filed