FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to methods for a vaccine therapy of herpetic infection. For this purpose, antigen-presenting dendritic cells (DC) taken from patient's blood are loaded with viral antigens that are originally found in a standard anti-herpetic vaccine representing suspended formalin-killed type I and II viruses of herpetic fever. The prepared vaccine is administered into the patient intracutaneously in 4-6 points along lymphatic collectors. The vaccine therapy course consists of 3-4 injections. A vaccine dosage interval makes 2 to 4 weeks. An initial vaccine dose makes 1×106-2×106 DC; for the second administration, the dose is increased twice; for the third administration the dose is increased 4 times as compared to the first administration.
EFFECT: invention enables providing vaccination both in the acute period, and in the remission, as well as prolonging the remission three times by reducing a recurrence rate.
1 ex, 2 tbl
Title | Year | Author | Number |
---|---|---|---|
METHOD OF TREATMENT OF PATIENTS WITH HERPES VIRUS INFECTION USING IN VITRO ACTIVATED AUTOLOGICAL LYMPHOCYTES | 2022 |
|
RU2799141C2 |
METHOD OF TREATING INFECTIONS INDUCED BY HERPES SIMPLEX VIRUSES TYPE I AND II, CYTOMEGALOVIRUS AND EPSTEIN-BARR VIRUS | 2008 |
|
RU2391981C2 |
METHOD FOR IMMUNOTHERAPY OF CHRONIC REFRACTORY HERPES VIRUS INFECTION | 2011 |
|
RU2485962C1 |
VACCINE AGAINST HERPES SIMPLEX VIRUS TYPE 2: COMPOSITIONS AND METHODS FOR TRIGGERING IMMUNE RESPONSE | 2010 |
|
RU2585961C9 |
DIAGNOSTIC TECHNIQUE FOR REMITTED GENITAL AND UROGENITAL HERPETIC INFECTION | 2010 |
|
RU2429781C1 |
METHOD OF TREATING AFFECTION OF VEGETATIVE PARASYMPATHETIC NODES OF HEAD OF HERPES-VIRUS ETIOLOGY | 2013 |
|
RU2538083C1 |
METHOD OF ACTIVATING FACTORS OF ANTIVIRAL PROTECTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE | 2015 |
|
RU2591809C1 |
METHOD OF TREATING RECURRENT GENITAL HERPES WITH CHRONIC FATIGUE SYMPTOMS | 2012 |
|
RU2492861C1 |
METHOD FOR TREATING RECURRENT HERPETIC STOMATITIS CASES AGGRAVATED BY SOMATOPHOROUS PAIN DISORDER | 2005 |
|
RU2304971C2 |
PHARMACEUTICAL COMPOSITION FOR PRODUCING ANTIHERPETIC MIXED VACCINE AND BASED DOSAGE FORM | 2014 |
|
RU2552341C1 |
Authors
Dates
2014-04-27—Published
2012-08-14—Filed