METHOD FOR VACCINE THERAPY OF HERPETIC INFECTION Russian patent published in 2014 - IPC A61K39/245 A61P31/22 

Abstract RU 2514034 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to methods for a vaccine therapy of herpetic infection. For this purpose, antigen-presenting dendritic cells (DC) taken from patient's blood are loaded with viral antigens that are originally found in a standard anti-herpetic vaccine representing suspended formalin-killed type I and II viruses of herpetic fever. The prepared vaccine is administered into the patient intracutaneously in 4-6 points along lymphatic collectors. The vaccine therapy course consists of 3-4 injections. A vaccine dosage interval makes 2 to 4 weeks. An initial vaccine dose makes 1×106-2×106 DC; for the second administration, the dose is increased twice; for the third administration the dose is increased 4 times as compared to the first administration.

EFFECT: invention enables providing vaccination both in the acute period, and in the remission, as well as prolonging the remission three times by reducing a recurrence rate.

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RU 2 514 034 C2

Authors

Chkadua Georgij Zurabovich

Borunova Anna Anatol'Evna

Ignat'Ev Il'Ja Vladimirovich

Zhordania Kirill Iosifovich

Pajanidi Julija Gennadievna

Dolgopolov Igor' Stanislavovich

Dates

2014-04-27Published

2012-08-14Filed