FIELD: medicine.
SUBSTANCE: method involves administering 3% hydrochloric acid into rats' duodenal submucosa through a puncture of an abdominal side wall. A laparotomy involves fixing an intestine preliminary with interrupted sutures applied through serous, muscular and submucosal duodenal layers. Fixing is performed so that to fix the jth intestinal circle. Seven to ten days after the laparotomy, a hydrochloric acid solution in a dose of 50 mcl is administered into three points by placing a needle tip first on an intestinal wall opposite to the puncture, thereafter moving it on the duodenal periphery at 45° by needle inclination. The administration is performed five times every 7 days.
EFFECT: method enables inducing the local cicatrical-ulcerous duodenal stenosis in each case of the conducted experiment.
1 dwg
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