METHOD FOR PREPARING ANTIULCER GASTRORETENTIVE AGENT Russian patent published in 2014 - IPC A61K36/76 A61K9/20 A61P1/04 

Abstract RU 2531092 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the pharmaceutical industry, particularly to a method for preparing an antiulcer gastroretentive agent. A method for preparing the antiulcer gastroretentive agent by extracting asp bark in the certain environment, adding guar gum (guar) and carboxymethyl cellulose sodium salt (Na-CMC) in the certain environment to the dry asp bark extract; the prepared mixture is agitated until smooth and subject to dry granulation by pre-moulding; the mould bars are ground, and the prepared granulate is tabletted.

EFFECT: method for preparing the antiulcer gastroretentive agent provides higher antiulcer action ensured by using the more advanced dosage form having a higher dose of the dry asp bark extract able to be retained in the stomach for a long time and regulating the release of the active substance.

19 dwg

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RU 2 531 092 C1

Authors

Turetskova Vera Feopenovna

Makarova Olesja Gennad'Evna

Lobanova Anastasija Jur'Evna

Talykova Nadezhda Mikhajlovna

Krylova Svetlana Gennad'Evna

Zueva Elena Petrovna

Dates

2014-10-20Published

2013-07-25Filed