FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to the pharmaceutical industry, particularly to a method for preparing an antiulcer gastroretentive agent. A method for preparing the antiulcer gastroretentive agent by extracting asp bark in the certain environment, adding guar gum (guar) and carboxymethyl cellulose sodium salt (Na-CMC) in the certain environment to the dry asp bark extract; the prepared mixture is agitated until smooth and subject to dry granulation by pre-moulding; the mould bars are ground, and the prepared granulate is tabletted.
EFFECT: method for preparing the antiulcer gastroretentive agent provides higher antiulcer action ensured by using the more advanced dosage form having a higher dose of the dry asp bark extract able to be retained in the stomach for a long time and regulating the release of the active substance.
19 dwg
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Authors
Dates
2014-10-20—Published
2013-07-25—Filed