FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and medicine, and concerns a pharmaceutical composition for intrajejunal administration for reducing an undesirable high serum glucose or reducing undesirable high peak serum insulin, which contains an active compound which is a representative of the calcitonin family, however is not amylin, and which is a modified representative of the calcitonin family, which has an amino acid homology of at least 75% with calcitonin, however not with amylin, and which is modified by adding, substituting or deleting amino acids and preserving an ability to bind and activate a calcitonin receptor, or a non-peptide low-molecular molecule of a calcitonin receptor agonist.
EFFECT: invention enables reducing the undesirable high serum glucose concentration.
9 cl, 12 dwg, 5 ex
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Authors
Dates
2014-12-27—Published
2010-03-10—Filed