METHOD FOR ENDOTHELIAL DYSFUNCTION CORRECTION Russian patent published in 2015 - IPC A61K39/395 A61P9/14 

Abstract RU 2541166 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to experimental cardiology and pharmacology, and concerns the endothelial dysfunction correction. That is ensured by a 28-day intragastric administration of a mixture of homeopathic dilutions of vascular endothelial growth factor (VEGF) monoclonal antibodies 2 times a day in a dose of 4.5 mg/kg with underlying intraperitoneal administration of L-NAME 12.5 mg/kg a day into white Wistar rats.

EFFECT: administering the homeopathic dilutions of the VEGF monoclonal antibodies prevents developing the L-NAME induced endothelial dysfunction in the specific experimental environment.

5 cl, 3 ex, 3 tbl

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RU 2 541 166 C2

Authors

Ehpshtejn Oleg Il'Ich

Sergeeva Svetlana Aleksandrovna

Zabolotneva Julija Aleksandrovna

Dates

2015-02-10Published

2011-04-28Filed