FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to experimental cardiology and pharmacology, and concerns the endothelial dysfunction correction. That is ensured by a 28-day intragastric administration of a mixture of homeopathic dilutions of vascular endothelial growth factor (VEGF) monoclonal antibodies 2 times a day in a dose of 4.5 mg/kg with underlying intraperitoneal administration of L-NAME 12.5 mg/kg a day into white Wistar rats.
EFFECT: administering the homeopathic dilutions of the VEGF monoclonal antibodies prevents developing the L-NAME induced endothelial dysfunction in the specific experimental environment.
5 cl, 3 ex, 3 tbl
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Authors
Dates
2015-02-10—Published
2011-04-28—Filed