METHOD OF TREATING CHRONIC INFLAMMATORY PERIODONTAL DISEASES CAUSED BY YEAST-LIKE CANDIDA FUNGI DEPENDING ON THE CONDITION OF FREE-RADICAL OXIDATION OF ORAL FLUID (VERSIONS) Russian patent published in 2016 - IPC A61N1/30 A61N2/04 A61N5/67 A61K31/155 A61K31/44 A61K31/711 A61K36/28 A61P1/02 A61H35/00 A61B10/00 

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to therapeutic dentistry and laboratory diagnostics, and can be used for treating chronic inflammatory periodontal diseases caused by yeast-like Candida fungi. For this purpose there are presented two versions of the treatment method. One performs luminol-dependant chemiluminescence of oral fluid. One determines values of the maximum flash and total luminescence. In case of the first variant upon detection of increased state of free-radical oxidation of oral fluid antioxidant therapy is performed. For this purpose, there is conducted transverse electrophoresis of 0.25 % solution of sodium deoxyribonuclease on gingival mucosa at current intensity of 0.5-1 mA, then polarity is changed, starting with the positive pole, for 8-10 minutes; the course consists of 4 procedures made every second day. Mouth is also bathed in water solution of 0.25 % sodium deoxyribonuclease. Used is a toothpaste and mouthwash “Mexidol dent” during 8-12 days. In case of the second variant upon detection of decreased state of free-radical oxidation of oral fluid, pro-oxidant therapy is conducted. For this purpose, there is conducted transverse electrophoresis of 0.25 % solution of sodium deoxyribonuclease on gingival mucosa at current intensity of 0.5-1 mA, then polarity is changed, starting with the positive pole, for 8-10 minutes; the course consists of 4 procedures made every second day. Also, in the zone of gums projection, there is conducted magnet-IR laser therapy (MIRL-therapy) with the help of laser “Optodan” with a periodontal attachment, mode - 2-2,000 Hz by segments, 2 minutes per segment, not more than 12 minutes, the course of consists of 4 procedures performed every second day. Mouth is also bathed in water solution of 0.25 % sodium deoxyribonuclease. Used is a toothpaste and mouthwash “Parodontax” during 8-12 days.

EFFECT: variants of the method provide a simplified and shorter duration of treatment due to adequate complex prolonged exposure of all links of the disease depending on the condition of free-radical oxidation of oral cavity.

2 cl, 2 ex