VACCINE INFLUENZA VIRUS STRAIN A/17/HONGKONG/2014/8296 (H3N2) FOR PREPARING LIVE INFLUENZA INTRANASAL VACCINE FOR ADULTS AND CHILDREN Russian patent published in 2017 - IPC C12N7/00 A61K39/145 

Abstract RU 2606019 C1

FIELD: medicine.

SUBSTANCE: invention refers to medical virology and concerns influenza virus strain. Disclosed a vaccine strain A/17/Hongkong/2014/8296 (H3N2)-reassortant, produced by crossing "wild" virus A/Hongkong/4801/2014 (H3N2) with cold-adaptive heat-sensitive virus A/Leningrad/134/17/57 (H2N2) – attenuation donor, safe for humans. Presented strain A/17/Hongkong/2014/8296 (H3N2) actively propagated in chicken embryos at optimal temperature of 32 °C, characterized by temperature sensitivity and cold adaptation and safety for laboratory animals. Strain is deposited in the State collection of viruses FGBU "FNICEM nam. N.F. Gamalei" of the Ministry of Health of Russia, Institute of virology nam. D.I. Ivanovskogo under № 2818.

EFFECT: invention can be used in practical health services for preventing influenza incidence in adults and children by a live influenza intranasal vaccine.

1 cl, 1 dwg, 5 tbl

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RU 2 606 019 C1

Authors

Bazhenova Ekaterina Andreevna

Kiseleva Irina Vasilevna

Matyushenko Viktoriya Arkadevna

Fedorova Ekaterina Alekseevna

Rudenko Larisa Georgievna

Dates

2017-01-10Published

2016-03-10Filed