APPLICATION OF FLECAINIDE AS ANTICONNEXIN AGENT AND METHOD OF POTENTIATION OF EFFECTS OF PSYCHOTROPIC MEDICINES Russian patent published in 2018 - IPC A61K31/4458 A61K31/165 A61P25/00 A61P25/28 

Abstract RU 2661026 C2

FIELD: medicine.

SUBSTANCE: provided: therapeutic composition comprising flecainide and at least one psychotropic drug modafinil; combined preparation containing flecainide and modafinil for the prevention and/or treatment of increased daytime sleepiness, sleep disorders, insufficient sleep duration, sleep apnoea syndrome; combined preparation of the same composition for the prevention and/or treatment of narcolepsy of attention deficit disorder with hyperactivity of post-traumatic stress disorder, disorders usually accompanied by drowsiness or drowsiness in Parkinson's disease; combined preparation of the same composition for the prevention and/or treatment of mood disorders, anxiety disorders, schizophrenia, depression, feelings of general malaise, dementia, bipolar disorder, bulimia, manic episode, obsessive-compulsive disorder, dependence or addiction to games, drugs, alcohol, tobacco.

EFFECT: technical result: anti-arrhythmic means of flecainide with anticonnexin activity potentiates the pro-amnestic or locomotor effects of the psychoactive drug modafinil, reduces the number of sleep episodes.

14 cl, 7 dwg, 5 ex, 1 tbl

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RU 2 661 026 C2

Authors

Muton Frank

Sharveria Mate

Dates

2018-07-11Published

2014-07-24Filed