AGENT WITH A GLYCOSYLATED POLYPEPTIDE AND A METHOD FOR PRODUCTION THEREOF Russian patent published in 2020 - IPC A61K9/08 A61K38/00 A61P29/00 

Abstract RU 2712235 C1

FIELD: pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry and represents an anti-inflammatory medicinal agent for intranasal application in the form of an aqueous solution in therapy of post-inflammatory complications, containing 100.0 ml of water: 0.001–0.500 g of glycosylated polypeptides recovered from fresh, frozen or dried insides of Strongylocentrotus droebachiensis sea urchins with molecular weight 5.5–7.0 kDa, 0.05–0.20 g of bioadhesive component-polycarbophil, 1.0–2.5 g of glycerin, 0.025–0.15 g of disodium edetate dihydrate, 0.005–0.02 g of benzalkonium chloride and sodium hydroxide solution, providing pH 6–7.

EFFECT: invention provides storage-stable and non-toxic aqueous glycosylated polypeptides for intranasal application, as well as an extended range of anti-inflammatory agents used in therapy of post-inflammatory complications.

6 cl, 7 ex, 2 tbl, 5 dwg

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Authors

Pozharitskaya Olga Nikolaevna

Demchenko Dmitrij Valentinovich

Makarov Valerij Gennadevich

Makarova Marina Nikolaevna

Shikov Aleksandr Nikolaevich

Katelnikova Anastasiya Evgenevna

Dates

2020-01-27Published

2019-05-16Filed