EphA4 ANTIBODY Russian patent published in 2020 - IPC C07K16/28 C12N5/10 C12N15/13 C12N15/63 C12P21/08 A61K39/395 A61P25/28 A61P21/02 

Abstract RU 2719158 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention relates to immunology. Antibody to EphA4 and EphA4-binding fragment are presented. Also disclosed is a pharmaceutical composition, a nucleic acid, an expression vector, a host cell and a method of producing an antibody to the EphA4 and EphA4-binding fragment.

EFFECT: present invention can find further application in therapy of various conditions, particularly amyotrophic lateral sclerosis.

15 cl, 20 dwg, 8 tbl, 20 ex

Similar patents RU2719158C2

Title Year Author Number
EphA4 ANTIBODY 2020
  • Inoue, Eiji
  • Yamada, Akio
  • Kawakatsu, Tomomi
  • Imai, Toshio
  • Deguchi, Maki
  • Nakatani, Aki
RU2816371C2
ANTIBODIES AGAINST SIGNAL-REGULATORY ALPHA PROTEIN AND THEIR APPLICATION METHODS 2017
  • Pons, Jaume
  • Sim, Bang Janet
  • Wan, Hong
  • Kuo, Tracy Chia-Chien
  • Kauder, Steven Elliot
  • Harriman, William Don
  • Izquierdo, Shelley
RU2771964C2
ANTIBODY CAPABLE OF BINDING TO THYMIC STROMAL LYMPHOPOIETIN, AND USE THEREOF 2020
  • Shi Tszinpin
  • In Khua
  • Li Tintin
  • Van Ifan
  • Yan Gujmej
  • Ge Khu
  • Tao Vejkan
RU2825304C2
BISPECIFIC ANTIBODY AGAINST RABIES VIRUS AND ITS APPLICATION 2019
  • Liu Zhigang
  • Hao Xiaobo
  • Liu Yulan
  • Guo Jingjing
RU2764740C1
CONNECTIVE TISSUE GROWTH FACTOR ANTIBODY AND USE THEREOF 2020
  • Fu, Yayuan
  • Ma, Syaoli
  • Ge, Khu
  • Tao, Vejkan
RU2819228C2
HIGH-AFFINITY ANTI-PD-1 AND ANTI-LAG-3 ANTIBODIES AND BISPECIFIC BINDING PROTEINS OBTAINED FROM THEM 2019
  • Wu, Xuan
  • Gong, Shiyong
  • Wu, Chengbin
RU2782381C2
ANTIBODY TO B7-H4, ITS ANTIGEN-BINDING FRAGMENT AND ITS PHARMACEUTICAL USE 2019
  • Bao Rudi
  • Hua Haiqing
  • Liu Suxia
  • Zhang Fujun
  • Wang Ting
RU2792748C2
ANTIBODIES AGAINST CXCR2 AND THEIR USE 2019
  • Chen, Doris, Shim Siew
  • Poulton, Lynn, Dorothy
  • Clarke, Adam
  • Laine, David, Jose Simon
  • Pollard, Matthew
  • Cooksey, Bridget, Ann
  • Doyle, Anthony
  • Gill, Jason, William
RU2807067C2
ANTIBODIES TO MYOSTATIN, POLYPEPTIDES CONTAINING FC-REGION VARIANTS, AND THEIR APPLICATION METHODS 2016
  • Kuramoti Tajti
  • Igava Tomoyuki
  • Katada Khitosi
  • Khori Yudzi
RU2789884C2
BISPECIFIC FUSION PROTEIN AND ITS USE 2021
  • Fang, Jianmin
RU2801528C2

RU 2 719 158 C2

Authors

Taguchi, Ryota

Imai, Toshio

Inoue, Eiji

Yamada Akio

Nakatani, Aki

Hirayama, Toshifumi

Ono, Yuichi

Ito, Shunsuke

Dates

2020-04-17Published

2016-09-06Filed