SELECTIVE COMPOUNDS OF YY PEPTIDE AND USE THEREOF Russian patent published in 2020 - IPC C07K14/575 A61K38/22 A61K47/54 A61P3/04 

Abstract RU 2726777 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to modified derivative peptide YY (PYY), and can be used in medicine. Compound of the present invention is PYY with amino acid modifications of Lys7/10, Trp30 and Leu31 and, in addition to them, Ile22 and/or Tyr28 with respect to native protein, to which a modifying group of lipid nature is bonded by the ε-amino group Lys7/10.

EFFECT: compound of the present invention can act as a selective Y2-receptor agonist.

33 cl, 5 tbl, 4 ex

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RU 2 726 777 C2

Authors

Estergaard Seren

Essen Karsten

Vulff Birigtte Skellerup

Sanfridson Annika

Dates

2020-07-15Published

2016-06-13Filed