FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly a test system for analyzing HLA-compatibility for use within the framework of a single-gene disorder PGD for selecting an embryo most suitable as a donor to a patient relative. Within the test system development high specificity and efficiency were shown, as well as versatility with respect to bio-samples of different types: single cells, product of full-genomic amplification, total DNA recovered from different tissues.
EFFECT: using the developed test system, preimplantation genetic testing for HLA-compatibility of embryos not inheriting the disease, for a family in which a child suffering a monogenic disease requires an HLA-compatible donor.
1 cl, 2 tbl, 2 ex
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