COMPOSITION OF NEUREGULIN PREPARATION Russian patent published in 2020 - IPC A61K38/18 A61K47/42 A61K47/12 A61P9/04 

Abstract RU 2738158 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention refers to treating cardiovascular disease. Liquid pharmaceutical composition of neuregulin (NRG) contains: (a) NRG polypeptide; (b) a pH buffer agent; (c) a stabilizer; (d) sodium chloride, wherein said composition has pH of 2–5.7, where the NRG polypeptide concentration is in the concentration range of 0.01–0.99 g/l, the pH-buffer agent concentration is in range of 0.1–500 mM, where the stabilizer is in concentration of 0.1–200 g/l, where sodium chloride is in the concentration range of 100–500 mM.

EFFECT: invention provides treating a patient suffering or at risk of developing heart failure.

9 cl, 18 tbl, 5 ex, 14 dwg

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RU 2 738 158 C2

Authors

Chzhou Mindun

Dates

2020-12-08Published

2014-12-17Filed