DEUTERATED DERIVATIVES OF 2-(IMIDAZOLE-4-YL)-ETHANAMIDE PENTANEDIOIC-1,5 ACID Russian patent published in 2022 - IPC C07D233/24 C07K5/06 A61K31/4164 A61P11/00 

Abstract RU 2783866 C2

FIELD: organic chemistry; pharmaceutics.

SUBSTANCE: invention relates to organic chemistry and pharmaceutics, and it is deuterated derivatives of 2-(imidazole-4-yl)-ethanamide pentanedioic-1,5 acid of the formula I, where R is H or D, provided that at least one R is D, for the treatment or prevention of diseases of the upper respiratory tract.

EFFECT: long-term average time of staying in the body, stability, and preservation of pharmacological activity, provided by a deuterated derivative of 2-(imidazole-4-yl)-ethanamide pentanedioic-1,5 acid of the formula I.

1 cl, 2 tbl, 1 ex

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Authors

Vladykin Aleksandr Lvovich

Zakharova Ekaterina Konstantinovna

Pereverzev Anton Petrovich

Porokhnya Mariya Viktorovna

Dates

2022-11-21Published

2021-04-01Filed