FIELD: organic chemistry; pharmaceutics.
SUBSTANCE: invention relates to organic chemistry and pharmaceutics, and it is deuterated derivatives of 2-(imidazole-4-yl)-ethanamide pentanedioic-1,5 acid of the formula I, where R is H or D, provided that at least one R is D, for the treatment or prevention of diseases of the upper respiratory tract.
EFFECT: long-term average time of staying in the body, stability, and preservation of pharmacological activity, provided by a deuterated derivative of 2-(imidazole-4-yl)-ethanamide pentanedioic-1,5 acid of the formula I.
1 cl, 2 tbl, 1 ex
Title |
Year |
Author |
Number |
NOVEL 2-(IMIDAZOL-4-YL)-ETHANAMIDE PENTANEDIOIC-1,5 ACID COMPOSITIONS FOR TREATING AND PREVENTING VIRAL DISEASES |
2020 |
- Nebolsin Vladimir Evgenevich
- Pereverzev Anton Petrovich
|
RU2746692C1 |
GLUTARIMIDE DERIVATIVES, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON, SYNTHESIS METHODS THEREOF |
2015 |
- Nebolsin Vladimir Evgenevich
- Kromova Tatyana Aleksandrovna
- Zheltukhina Galina Aleksandrovna
|
RU2610274C2 |
GLUTARIMIDE DERIVATIVE, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON, SYNTHESIS METHOD THEREOF |
2015 |
- Nebolsin Vladimir Evgenevich
- Kromova Tatyana Aleksandrovna
- Zheltukhina Galina Aleksandrovna
|
RU2610275C2 |
GLUTARIMIDE DERIVATIVE, USE THEREOF, PHARMACEUTICAL COMPOSITION BASED THEREON, SYNTHESIS METHODS THEREOF |
2013 |
- Nebolsin Vladimir Evgenevich
- Kromova Tatyana Aleksandrovna
- Zheltukhina Galina Aleksandrovna
|
RU2610276C1 |
2-ARYL-SUBSTITUTED N-ARYLIMIDAZOLINES, SELECTIVE CYCLOOXYGENASE-2 INHIBITORS, METHODS FOR PRODUCTION AND USE THEREOF |
2014 |
- Dorogov Mikhail Vladimirovich
- Krasavin Mikhail Jur'Evich
|
RU2565667C1 |
SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, SYNTHESIS AND APPLICATION METHOD |
2010 |
- Ivashchenko Aleksandr Vasil'Evich
- Bychko Vadim Vasil'Evich
- Mit'Kin Oleg Dmitrievich
|
RU2452735C1 |
NOVEL FORMULATIONS OF 2-(IMIDAZOL-4-YL)-ETHANAMIDE OF PENTANEDIOIC ACID FOR TREATMENT AND PREVENTION OF VIRAL DISEASES |
2020 |
- Pereverzev Anton Petrovich
|
RU2791902C2 |
NOVEL 2-(IMIDAZOL-4-YL)-ETHANAMIDE OF PENTANDIOIC-1,5 ACID COMPOSITIONS FOR TREATING AND PREVENTING VIRAL DISEASES |
2019 |
- Pereverzev Anton Petrovich
|
RU2745265C2 |
NEW FORMULATIONS OF 2-(IMIDAZOLE-4-YL)-ETHANAMIDE PENTANEDIOIC-1,5 ACID FOR THE TREATMENT AND PREVENTION OF VIRAL DISEASES |
2020 |
- Pereverzev Anton Petrovich
|
RU2782532C2 |
BENZIMIDAZOLE DERIVATIVES EFFECTIVE IN TREATING RESPIRATORY SYNCYTIAL VIRUS INFECTION |
2012 |
|
RU2612530C2 |