REASSORTANT STRAIN OF INFLUENZA VIRUS A/17/NEWCASTLE/2018/22 (H3N2) FOR THE PRODUCTION OF LIVE INTRANASAL INFLUENZA VACCINE FOR ADULTS AND CHILDREN Russian patent published in 2022 - IPC C12N7/00 A61K39/145 

Abstract RU 2783887 C1

FIELD: medical virology.

SUBSTANCE: invention relates to medical virology. The proposed vaccine strain A/17/Newcastle/2018/22 (H3N2) is a reassortant obtained by crossing the epidemic virus A/Newcastle/82/2018 (H3N2) (A/South Australia/34/2019-like) with a cold-adapted temperature-sensitive virus A/Leningrad/134/17/57 (H2N2) - an attenuation donor, harmless to humans.

EFFECT: proposed strain can be used for the production of a live intranasal influenza vaccine for adults and children.

1 cl, 1 dwg, 5 tbl

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RU 2 783 887 C1

Authors

Stepanova Ekaterina Alekseevna

Krutikova Elena Vitalevna

Bazhenova Ekaterina Andreevna

Larionova Natalya Valentinovna

Kiseleva Irina Vasilevna

Isakova-Sivak Irina Nikolaevna

Rudenko Larisa Georgievna

Dates

2022-11-21Published

2022-04-15Filed