FIELD: biotechnology.
SUBSTANCE: group of inventions is described, including an antibody against human CD147 or its antigen-binding fragment, which activates signal transduction by means of CD147 (options), an antitumor composition containing the above-mentioned antibody, where tumor is tumor expressing CD147, a method for the treatment of tumor expressing CD147, and the use of an antibody, or its antigen-binding fragment, or a composition for the treatment of tumor, where tumor is tumor expressing CD147.
EFFECT: invention expands the arsenal of remedies against CD147.
34 cl, 50 dwg, 8 tbl, 26 ex
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