COMPOSITION FOR THE TREATMENT OF BIOTIN-DEFICIENT CONDITIONS IN CHILDREN, AS WELL AS A METHOD OF TREATMENT USING SUCH A COMPOSITION Russian patent published in 2023 - IPC A61K31/4188 A61K31/4415 A61K31/455 A61K31/51 A61K31/525 A61K31/197 A61K47/26 A61K47/36 A61K9/14 A61P25/00 

FIELD: medicine and pharmaceuticals.

SUBSTANCE: group of inventions can be used to treat biotin-deficient conditions in children of the first year of life and older. A composition for the treatment of biotin-deficient conditions in children of the first year of life and older is proposed, containing biotin, vitamins B1, B2, B3, B5, B6, B9, a filler, which is a mixture of dextrose and maltodextrin in a ratio of 1:1 by weight, with the following the ratio of components in grams per 1,000 g of the following mixture: Biotin — 2.5–10; B3-Nicotinamide — 0.488; B5-Calcium pantothenate — 0.12; B6-pyridoxine hydrochloride — 0.05; B1-Thiamin mononitrate — 0.04; B2-Riboflavin — 0.045; B9-Folic acid — 0.0106; filler — the rest. A method for treating biotin-deficient conditions in children of the first year of life and older includes adding the specified composition to a food product suitable for children of the first year of life and older, and a single dose of biotin of 2.5–20 mg, and the daily dose reaching 100 mg/day.

EFFECT: invention makes it possible to effectively and safely treat biotin-deficient conditions in children of the first year of life and older, and the indicated agent has a high solubility, which makes it possible to add it to breast milk substitutes and complementary foods.

3 cl, 3 ex