FIELD: biotechnology.
SUBSTANCE: present invention relates to the field and can be used in medicine. Invention discloses combinations containing leptin receptor antagonists, GDF8 and activin A, as well as methods of using them. There are also provided methods of treating malnutrition, cachexia and other conditions characterized by malnutrition and weight loss.
EFFECT: such compositions are effective, for example, to provide an increase in the mass of non-adipose body tissues at least partially due to the fat mass.
26 cl, 4 ex, 12 tbl
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